Professor Gordon Rustin qualified from the Middlesex Hospital, London in 1971. He was appointed Senior Lecturer in Medical Oncology at the Charing Cross Hospital in 1984 but moved full-time to Mount Vernon Hospital to become Director of Medical Oncology in 1995, where he was leading research and clinical trial of vascular disruptive agents. Professor Rustin is widely published, with over 320 papers to his name on the management of gynaecological cancers, germ cell tumours, the use of tumour markers, and on phase I, II, and III trials. He was awarded an honorary professorship in 2001 by UCL, later becoming the professor of cancer therapy at the Institute of Cancer Research.
He retired from the hospital in 2018 but continues his private practice at BMI Bishops Wood Hospital as well as medico-legal work, refereeing papers and lecturing.